Pipeline

Our Pipeline of Wholly Owned Assets and Partnered Programs

We’re building a comprehensive pipeline of drug candidates that deliver on the promise of modulating RNA biology for therapeutic benefit.

Target Target Class Indication Target-to-HTS Hit to Lead Lead Op Development Candidate Partner
elF4E Protein Oncology
c-MYC RNA Oncology
Regnase-1 Protein Immuno-oncology
Multiple Programs RNA Oncology
Multiple Targets RNA Undisclosed
Status Undisclosed
Multiple Targets RNA Undisclosed
Status Undisclosed
Ribometrix lab

Where We’re Starting

Our industry-leading RNA biology and drug discovery capabilities drive our unique approach to address targets considered “undruggable” by conventional methods: we modulate the biology of mRNAs, preventing the production of disease-driving proteins. This opens a new path to targeting the drivers of cancer and other diseases.

We are initially focused on mRNAs of undruggable proteins and RBPs linked to specific disease phenotypes. We are also using our proprietary AI/ML platform to identify high-value, clinically relevant RNA and RBP targets.